In letter clusters GCXTO, KGBXS, QMHDY, the number of letters between the consecutive letters of the letter clusters are 3, 4, 3, 4 respectively.
In RNIEX, the number of letters between E and X is 6.
$$\therefore\ $$RNIEX is the odd one among the given letter clusters.
Hence, the correct answer is Option C
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