Each letter is represented by their position in the English alphabetical series.
So, C= 3, A=1, T=20 = $$(3+1+20) = 24\times3=72$$
T=20, R=18, O=15, T=20
$$(20+18+15+20) = 73\times4=292$$
The pattern is after adding the sum is multiplied with the number of total alphabet,
S= 19, T=20, A=1, G=7 = $$(19+20+1+7)\times4=188$$
Ans: C
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